UV Raman spatially resolved melting dynamics of isotopically labeled polyalanyl peptide: Slow [alpha]-helix melting follows [3.sub.10]-helices and [pi]-bulges premelting

Article Abstract:

An investigation is done to determine the spatial dependence of the T-jump secondary structure relaxation of an isotopically labeled 21-residue, specifically, Ala peptide (AdP) by ultraviolet resonance Raman (UVRR). It is demonstrated that the folding mechanism of end residues of Ala-rich peptides vary substantially from that of middle residues with respect to various relative contribution of variety of 'alpha-helix-like' types to the melting kinetics.

Polypeptides, Thermal properties, Dynamics, Dynamics (Mechanics)

---

Peptide secondary structure folding reaction coordinate: Correlation between UV Raman amide III frequency, Psi Ramachandran angle, and hydrogen bonding

Article Abstract:

A study to quantitatively correlate the peptide bond AmIII frequency to its Psi Ramachandran angle and to the number and types of amide hydrogen bonds at different temperatures using UV resonance Raman (UVRR) spectroscopy is conducted. The results allow us to develop a family of relationships to directly estimate Psi Ramachandran angle from measured UVRR AmIII frequencies for peptide bonds with known hydrogen bonding.

Usage, Protein folding, Hydrogen bonding, Hydrogen bonds, Chemical properties

---

Uncoupled peptide bond vibrations in alpha-helical and polyproline II conformations of polyalanine peptides

Article Abstract:

The 204-nm UV resonance Raman spectra of the polyproline II and alpha-helical states of a 21-residue mainly alanine peptide is examined in different H2O/D2O mixtures is examined. The findings indicate that the UVR spectra of the AmIII and AmII' bands of both the PPII conformation and the alpha-helical conformation can be exactly modeled as the linear sum of the fully N-H protonated and N-D deuterated peptides.

Plastics Material and Resin Manufacturing, Pennsylvania, Plastics materials and resins, Polypropylene, Vibrational spectra

Similar abstracts:

• Abstracts: Ab initio modeling of CW-ESR spectra of the double spin labeled peptide Fmoc-[(Aib-Aib-TOAC).sub.2]-Aib-OMe in acetonitrile
• Abstracts: Adsorption of a cationic dye molecule on polystyrene microspheres in colloids: Effect of surface charge and composition probed by second harmonic generation
• Abstracts: Equilibrium and dynamics of soluble surfactant penetration into a Langmuir monolayer of a 2D aggregating homologue
• Abstracts: Glass transition dynamics and boiling temperatures of molecular liquids and their isomers. Debye type dielectric relaxation and the glass transition of alcohols
• Abstracts: Optimized intermolecular potential for aromatic hydrocarbons based on Anisotropic United Atoms. 2. alkylbenzenes and styrene

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.